Serum Amyloid A

Serum concentrations of haptoglobin and serum amyloid A in water buffaloes (Bubalus bubalis) with abomasal ulcer

To evaluate the serum concentrations of haptoglobin (Hp) and serum amyloid A (SAA) in water buffaloes with abomasal ulcers, the abomasums of 100 randomly selected water buffaloes were examined after slaughter. Type I abomasal ulcers were found in 56 out of 100 buffaloes. Serum concentrations of Hp and SAA were measured. There was no significant difference between affected and non-affected buffa...

Removal of Serum Amyloid A

Serum amyioid A (SAA) 1 is presumed to be the precursor for amyloid A protein, the main protein constituent found in the amyioid fibrils of reactive amyloidosis (1-3). In the mouse SAA is encoded by a family of three genes (Morrow, John F., personal communication). SAA1 and SAA2 are synthesized in the liver by hepatocytes (4-10) and are found circulating in nearly equal quantities associated wi...

Human serum amyloid A (SAA)

Serum amyloid A apol ipoprote in family consists of three members that in human beings are coded by different genes: SAA1, SAA2, and SAA4 (reviewed in 1-3). SAA1 and SAA2 are so-called acute phase isoforms. Their expression is increased in response to inflammation. SAA4 is a constitutive isoform, the expression of which does not change during an acute-phase response. In addition, one more relat...

Serum Amyloid A-Luciferase Transgenic

Tenomodulin, serum amyloid A and the serum amyloid A receptor selenoprotein S – implications for metabolic disease

Obesity and obesity-related metabolic diseases are associated with a low-grade inflammation, including slightly increased serum levels of the acute phase protein serum amyloid A (A-SAA). A-SAA is one amongst several adipose tissue (AT) produced proteins suggested to influence development of metabolic diseases. The A-SAA protein may have pro-atherogenic functions, and release of A-SAA from the A...